Metabolism and pharmacokinetics of morphine in neonates: A review
Morphine is an agonist of the µ and k receptors, whose activation results in analgesia. Morphine-like agonists act through the µ opioid receptors to cause pain relief, sedation, euphoria and respiratory depression. Morphine is glucuronidated and sulfated at positions 3 and 6; the plasma concentratio...
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| Format: | Article |
| Language: | English |
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Faculdade de Medicina / USP
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| Series: | Clinics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322016000800474&lng=en&tlng=en |