Transcription factors in Escherichia coli prefer the holo conformation.

The transcriptional regulatory network of Escherichia coli K-12 is among the best studied gene networks of any living cell. Transcription factors bind to DNA either with their effector bound (holo conformation), or as a free protein (apo conformation) regulating transcription initiation. By using Re...

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Bibliographic Details
Main Authors: Yalbi Itzel Balderas-Martínez, Michael Savageau, Heladia Salgado, Ernesto Pérez-Rueda, Enrique Morett, Julio Collado-Vides
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3680503?pdf=render