Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Summary: TxNIP (Thioredoxin-interacting protein) is considered as a potential drug target for type 2 diabetes. Although TxNIP expression is correlated with hyperglycemia and glucotoxicity in pancreatic β cells, its regulation in liver cells has been less investigated. In the current study, we aim at...

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Bibliographic Details
Main Authors: Benedicte Noblet, Fadila Benhamed, InSug O-Sullivan, Wenwei Zhang, Gaëlle Filhoulaud, Alexandra Montagner, Arnaud Polizzi, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Tarik Issad, Hervé Guillou, Catherine Bernard, Terry Unterman, Catherine Postic
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Molecular Physiology
Molecular Biology
Endocrinology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001863

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http://www.sciencedirect.com/science/article/pii/S2589004221001863

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