Regulation of localization and function of the transcriptional co-activator YAP by angiomotin

The Hippo-YAP pathway is a central regulator of cell contact inhibition, proliferation and death. There are conflicting reports regarding the role of Angiomotin (Amot) in regulating this pathway. While some studies suggest a YAP-inhibitory function other studies indicate Amot is required for YAP act...

Full description

Bibliographic Details
Main Authors: Susana Moleirinho, Sany Hoxha, Vinay Mandati, Graziella Curtale, Scott Troutman, Ursula Ehmer, Joseph L Kissil
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
YAP
Online Access:https://elifesciences.org/articles/23966