PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death

PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death

Castrate resistant prostate cancer in men shares several characteristics with canine prostate cancer (PCa). Due to current insufficient therapies, evaluating novel therapeutic agents for late-stage PCa is of considerable interest for both species. PDA indolylmaleimides showed anticancer effects in s...

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Bibliographic Details
Main Authors: Jan Torben Schille, Ingo Nolte, Julia Beck, Daria Jilani, Catrin Roolf, Anahit Pews-Davtyan, Arndt Rolfs, Larissa Henze, Matthias Beller, Bertram Brenig, Christian Junghanss, Ekkehard Schütz, Hugo Murua Escobar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Veterinary Science
Subjects:
mitotic death
mitotic slippage
whole transcriptome sequencing
human
dog
prostate cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.558135/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.558135/full

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