An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example

An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example

Abstract Background Target identification is necessary for the comprehensive inference of the mechanism of action of a compound. The application of computational methods to predict the targets of bioactive compounds saves cost and time in drug research and development. Therefore, we designed an inte...

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Bibliographic Details
Main Authors: Hao Sun, Yiting Shen, Guangwen Luo, Yuepiao Cai, Zheng Xiang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Bioinformatics
Subjects:
Target identification
Rhein
Ligand-protein docking
Network analysis
Enrichment analysis
SPR
Online Access:http://link.springer.com/article/10.1186/s12859-018-2346-4

Internet

http://link.springer.com/article/10.1186/s12859-018-2346-4

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