A Novel Approach for Quantifying Cancer Cells Showing Hybrid Epithelial/Mesenchymal States in Large Series of Tissue Samples: Towards a New Prognostic Marker

A Novel Approach for Quantifying Cancer Cells Showing Hybrid Epithelial/Mesenchymal States in Large Series of Tissue Samples: Towards a New Prognostic Marker

In cancer biology, epithelial-to-mesenchymal transition (EMT) is associated with tumorigenesis, stemness, invasion, metastasis, and resistance to therapy. Evidence of co-expression of epithelial and mesenchymal markers suggests that EMT should be a stepwise process with distinct intermediate states...

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Bibliographic Details
Main Authors: Louis Godin, Cédric Balsat, Yves-Rémi Van Eycke, Justine Allard, Claire Royer, Myriam Remmelink, Ievgenia Pastushenko, Nicky D’Haene, Cédric Blanpain, Isabelle Salmon, Sandrine Rorive, Christine Decaestecker
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
computational pathology
hybrid E/M state
partial EMT
prognosis
quantification
sequential immunohistochemistry
Online Access:https://www.mdpi.com/2072-6694/12/4/906

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https://www.mdpi.com/2072-6694/12/4/906

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