Effect of α-Bisabolol and Its β-Cyclodextrin Complex as TetK and NorA Efflux Pump Inhibitors in <i>Staphylococcus aureus</i> Strains

Effect of α-Bisabolol and Its β-Cyclodextrin Complex as TetK and NorA Efflux Pump Inhibitors in <i>Staphylococcus aureus</i> Strains

Efflux pumps are proteins present in the plasma membrane of bacteria, which transport antibiotics and other compounds into the extracellular medium, conferring resistance. The discovery of natural efflux pump inhibitors is a promising alternative. &#945;-Bisabolol is a sesquiterpene isolated fro...

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Bibliographic Details
Main Authors: Rafael Pereira da Cruz, Thiago Sampaio de Freitas, Maria do Socorro Costa, Antonia Thassya Lucas dos Santos, Fábia Ferreira Campina, Raimundo Luiz Silva Pereira, José Weverton Almeida Bezerra, Lucindo José Quintans-Júnior, Adriano Antunes De Souza Araújo, José Pinto De Siqueira Júnior, Marcello Iriti, Elena Maria Varoni, Irwin Rose Alencar De Menezes, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Antibiotics
Subjects:
resistance
antibiotics
sesquiterpene
bacteria
Online Access:https://www.mdpi.com/2079-6382/9/1/28

Internet

https://www.mdpi.com/2079-6382/9/1/28

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