Ovarian reserve of women with and without BRCA pathogenic variants: A systematic review and meta-analysis

Ovarian reserve of women with and without BRCA pathogenic variants: A systematic review and meta-analysis

Introduction: Preliminary clinical evidence suggests a detrimental effect of pathogenic variants of BRCA1 and 2 genes on fertility outcome. This meta-analysis evaluates whether women carrying BRCA mutations (BRCAm) have decreased ovarian reserve, in terms of Anti-Muellerian Hormone (AMH), compared t...

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Bibliographic Details
Main Authors: Maria Luisa Gasparri, Rosa Di Micco, Veronica Zuber, Katayoun Taghavi, Giampaolo Bianchini, Serena Bellaminutti, Francesco Meani, Rossella Graffeo, Massimo Candiani, Michael D. Mueller, Andrea Papadia, Oreste D. Gentilini
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Breast
Subjects:
AMH
Breast cancer
Ovarian reserve
BRCA1m
BRCA2m
BRCA pathogenic variants
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977621004628

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http://www.sciencedirect.com/science/article/pii/S0960977621004628

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