Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease

Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease

Upon activation, platelets release a host of soluble and vesicular signals, collectively termed the “platelet releasate” (PR). The contents of this PR play a significant role in haemostasis, inflammation, and pathologic sequelae. Despite this, proteomic studies investigating the PR in coronary arter...

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Bibliographic Details
Main Authors: Patricia B. Maguire, Martin E. Parsons, Paulina B. Szklanna, Monika Zdanyte, Patrick Münzer, Madhumita Chatterjee, Kieran Wynne, Dominik Rath, Shane P. Comer, Melanie Hayden, Fionnuala Ní Áinle, Meinrad Gawaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
platelets
platelet releasate
proteomics
mass spectrometry
acute coronary syndrome
stable coronary artery disease
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2020.00101/full

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https://www.frontiersin.org/article/10.3389/fcvm.2020.00101/full

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