Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis.

Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis.

CD11b+Gr1+ myeloid derived suppressor cells (MDSC) are known to be very potent suppressors of T cell immunity and can be further stratified into granulocytic MDSC and monocytic MDSC in mice based on expression of Ly6G or Ly6C, respectively. Here, using these markers and functional assays, we aimed t...

Full description

Bibliographic Details
Main Authors: Bastian Höchst, Julita Mikulec, Tania Baccega, Christina Metzger, Meike Welz, Julia Peusquens, Frank Tacke, Percy Knolle, Christian Kurts, Linda Diehl, Isis Ludwig-Portugall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4349817?pdf=render

Internet

http://europepmc.org/articles/PMC4349817?pdf=render

Similar Items