Excess Provisional Extracellular Matrix: A Common Factor in Bicuspid Aortic Valve Formation
A bicuspid aortic valve (BAV) is the most common cardiac malformation, found in 0.5% to 2% of the population. BAVs are present in approximately 50% of patients with severe aortic stenosis and are an independent risk factor for aortic aneurysms. Currently, there are no therapeutics to treat BAV, and...
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Format: | Article |
Language: | English |
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MDPI AG
2021-08-01
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Series: | Journal of Cardiovascular Development and Disease |
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Online Access: | https://www.mdpi.com/2308-3425/8/8/92 |