Pasteurella multocida Pm0442 Affects Virulence Gene Expression and Targets TLR2 to Induce Inflammatory Responses

Pasteurella multocida Pm0442 Affects Virulence Gene Expression and Targets TLR2 to Induce Inflammatory Responses

Pasteurella multocida is an important pathogenic bacterium of domestic animals. However, the mechanisms of infection are still poorly understood. Here, we found that Pm0442 was dramatically up-regulated in infected mice among 67 predicted lipoproteins of P. multocida serotype A CQ2 strain (PmCQ2). T...

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Bibliographic Details
Main Authors: Fang He, Xiaobin Qin, Na Xu, Pan Li, Xiaoyan Wu, Lijie Duan, Yiyang Du, Rendong Fang, Philip R. Hardwidge, Nengzhang Li, Yuanyi Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
Pasteurella multocida
Pm0442
virulence gene
TLR2
inflammatory responses
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01972/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01972/full

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