B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses

B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses

Hepatitis B virus (HBV) infection causes acute and chronic liver inflammation. Recent studies have demonstrated that some viral antigens can suppress host innate and adaptive immunity, and thus lead to HBV liver persistency. However, the cellular factors that can help host cells to clear HBV during...

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Bibliographic Details
Main Authors: Chun-Ta Lin, Yue-Ting Hsieh, Yeng-Jey Yang, Shih-Hui Chen, Cheng-Hsuan Wu, Lih-Hwa Hwang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
Hepatitis B virus (HBV)
B-cell lymphoma 6 (BCL6)
restriction factor
transcriptional repressor
HBV clearance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03253/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03253/full

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