Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study.

Plasma soluble Receptor for Advanced Glycation End-products (sRAGE) is a strong marker of vascular outcomes although evidence on the direction of association is mixed. Compared to whites, blacks have lower levels of sRAGE. We hypothesized that genetic determinants of sRAGE would help clarify the cau...

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Bibliographic Details
Main Authors: Nisa M Maruthur, Man Li, Marc K Halushka, Brad C Astor, James S Pankow, Eric Boerwinkle, Josef Coresh, Elizabeth Selvin, Wen Hong Linda Kao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4471120?pdf=render