Potentiation of Acetylcholine-Induced Relaxation of Aorta in Male UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) Rats: Sex-Specific Responses

Potentiation of Acetylcholine-Induced Relaxation of Aorta in Male UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) Rats: Sex-Specific Responses

Previous reports suggest that diabetes may differentially affect the vascular beds of females and males. The objectives of this study were to examine whether there were (1) sex differences in aortic function and (2) alterations in the relative contribution of endothelium-derived relaxing factors in...

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Bibliographic Details
Main Authors: Farjana Akther, Md Rahatullah Razan, Sonali Shaligram, James L. Graham, Kimber L. Stanhope, Kaitlin N. Allen, José Pablo Vázquez-Medina, Peter J. Havel, Roshanak Rahimian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
sex differences
aorta
type-2 diabetes
nitric oxide
insulin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.616317/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.616317/full

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