Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer’s Disease

Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer’s Disease

The lack of effective disease-modifying therapeutics to tackle Alzheimer’s disease (AD) is unsettling considering the actual prevalence of this devastating neurodegenerative disorder worldwide. Intermittent hypoxic conditioning (IHC) is a powerful non-pharmacological procedure known to enhance brain...

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Bibliographic Details
Main Authors: Sónia C. Correia, Nuno J. Machado, Marco G. Alves, Pedro F. Oliveira, Paula I. Moreira
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
brain cortex
cognition
intermittent hypoxic conditioning
mitochondrial bioenergetics and dynamics
synaptic integrity
Online Access:https://www.mdpi.com/1422-0067/22/1/461

Internet

https://www.mdpi.com/1422-0067/22/1/461

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