A Variant of the Histone-Binding Protein sNASP Contributes to Mouse Lupus

The Sle2c1rec1c (rec1c) sublocus is derived from the mouse lupus susceptibility 2 (Sle2) locus identified in the NZM2410 model. Our current study dissected the functional characters and the genetic basis of the rec1c locus relative to lupus when co-expressed with the Faslpr mutation, an established...

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Bibliographic Details
Main Authors: Jiyu Ju, Jia Xu, Yaoqiang Zhu, Xiaoyan Fu, Laurence Morel, Zhiwei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00637/full