Drosophila interspecific hybrids phenocopy piRNA-pathway mutants.

The Piwi-interacting RNA (piRNA) pathway defends the germline of animals from the deleterious activity of selfish transposable elements (TEs) through small-RNA mediated silencing. Adaptation to novel invasive TEs is proposed to occur by incorporating their sequences into the piRNA pool that females...

Full description

Bibliographic Details
Main Authors: Erin S Kelleher, Nathaniel B Edelman, Daniel A Barbash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3506263?pdf=render