Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex trait/disease and the genetic correlation between two complex traits/diseases using genome-wide single nucleotide polymorphism (SNP) data in unrelated individuals. Here we use analytical derivations and...

Full description

Bibliographic Details
Main Authors: Peter M Visscher, Gibran Hemani, Anna A E Vinkhuyzen, Guo-Bo Chen, Sang Hong Lee, Naomi R Wray, Michael E Goddard, Jian Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3983037?pdf=render

Internet

http://europepmc.org/articles/PMC3983037?pdf=render

Similar Items