REV-ERB agonist suppresses IL-17 production in γδT cells and improves psoriatic dermatitis in a mouse model

Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperplasia and cellular infiltration. Studies have shown that disease development depends on proinflammatory cytokines, such as interleukin (IL)-23 and IL-17. It has been suggested that IL-23 produced by innate immune cells...

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Bibliographic Details
Main Authors: Shangyi Wang, Mina Kozai, Hironobu Mita, Zimeng Cai, Md. Abdul Masum, Osamu Ichii, Kensuke Takada, Mutsumi Inaba
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221010672