Abnormalities in lysine degradation are involved in early cardiomyocyte hypertrophy development in pressure-overloaded rats

Abnormalities in lysine degradation are involved in early cardiomyocyte hypertrophy development in pressure-overloaded rats

Abstract Background Cardiomyocyte metabolism changes before cardiac remodeling, but its role in early cardiac hypertrophy detection remains unclear. This study investigated early changes in plasma metabolomics in a pressure-overload cardiac hypertrophy model induced by transverse aortic constriction...

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Bibliographic Details
Main Authors: Jialing Liu, Junhao Hu, Lanlan Tan, Qi Zhou, Xiaojing Wu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Cardiovascular Disorders
Subjects:
Cardiac hypertrophy
Pressure overload
Lysine degradation
Metabolomics
Nonenergetic metabolism
Online Access:https://doi.org/10.1186/s12872-021-02209-w

Internet

https://doi.org/10.1186/s12872-021-02209-w

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