Statistical approaches to identify subgroups in meta-analysis of individual participant data: a simulation study

Statistical approaches to identify subgroups in meta-analysis of individual participant data: a simulation study

Abstract Background Individual participant data meta-analysis (IPD-MA) is considered the gold standard for investigating subgroup effects. Frequently used regression-based approaches to detect subgroups in IPD-MA are: meta-regression, per-subgroup meta-analysis (PS-MA), meta-analysis of interaction...

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Bibliographic Details
Main Authors: Michail Belias, Maroeska M. Rovers, Johannes B. Reitsma, Thomas P. A. Debray, Joanna IntHout
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Medical Research Methodology
Subjects:
Subgroups
Simulation
Individual participant data
Effect modification
Meta-analysis
Statistical approaches
Online Access:http://link.springer.com/article/10.1186/s12874-019-0817-6

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http://link.springer.com/article/10.1186/s12874-019-0817-6

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