Role of tubular epithelial arginase-II in renal inflammaging

Abstract The aging kidney undergoes complex changes and is vulnerable to injury and development of chronic kidney disease (CKD) with preponderance affecting more women than men. Evidence has been presented that the type-II L-arginine:ureohydrolase, arginase-II (Arg-II) plays a role in the accelerati...

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Bibliographic Details
Main Authors: Ji Huang, Xiujie Liang, Diogo Ladeiras, Benoit Fellay, Xiu-Fen Ming, Zhihong Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-021-00057-8