In Vitro DNA-Binding, Anti-Oxidant and Anticancer Activity of Indole-2-Carboxylic Acid Dinuclear Copper(II) Complexes

In Vitro DNA-Binding, Anti-Oxidant and Anticancer Activity of Indole-2-Carboxylic Acid Dinuclear Copper(II) Complexes

Indole-2-carboxylic acid copper complex (ICA-Cu) was successfully prepared and characterized through elemental analysis, IR, UV-Vis, 1H-NMR, TG analysis, and molar conductance, and its molecular formula was [Cu2(C9H6O2N)4(H2O)2]·2H2O. The binding ability of ICA-Cu to calf thymus DNA (CT-DNA) was exa...

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Bibliographic Details
Main Authors: Xiangcong Wang, Maocai Yan, Qibao Wang, Huannan Wang, Zhengyang Wang, Jiayi Zhao, Jing Li, Zhen Zhang
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
DNA-binding
antioxidant
anticancer
indole-2-carboxylicacid
copper(II) complexes
Online Access:http://www.mdpi.com/1420-3049/22/1/171

Internet

http://www.mdpi.com/1420-3049/22/1/171

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