Identifying modularity structure of a genetic network in gene expression profile data

Aim of this paper is to define a new statistical framework to identify central modules in Gaussian Graphical Models (GGMs) estimated by gene expression data measured on a sample of patients with negative molecular response to Imatinib. Imatinib is a drug used to treat certain types of cancer that in...

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Bibliographic Details
Main Authors: Luigi Augugliaro, Angelo M. Mineo
Format: Article
Language:English
Published: University of Bologna 2013-05-01
Series:Statistica
Subjects:
Online Access:http://rivista-statistica.unibo.it/article/view/4345