LC-MS/MS Analysis Unravels Deep Oxidation of Manganese Superoxide Dismutase in Kidney Cancer

LC-MS/MS Analysis Unravels Deep Oxidation of Manganese Superoxide Dismutase in Kidney Cancer

Manganese superoxide dismutase (MNSOD) is one of the major scavengers of reactive oxygen species (ROS) in mitochondria with pivotal regulatory role in ischemic disorders, inflammation and cancer. Here we report oxidative modification of MNSOD in human renal cell carcinoma (RCC) by the shotgun method...

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Bibliographic Details
Main Authors: Zuohui Zhao, Kazem M. Azadzoi, Han-Pil Choi, Ruirui Jing, Xin Lu, Cuiling Li, Fengqin Wang, Jiaju Lu, Jing-Hua Yang
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:International Journal of Molecular Sciences
Subjects:
liquid chromatography-tandem mass spectrometry
MNSOD
oxidation
ROS
quantitative proteomics
Online Access:http://www.mdpi.com/1422-0067/18/2/319

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http://www.mdpi.com/1422-0067/18/2/319

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