Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro.

BACKGROUND: High dietary fructose has structural and metabolic cardiac impact, but the potential for fructose to exert direct myocardial action is uncertain. Cardiomyocyte functional responsiveness to fructose, and capacity to transport fructose has not been previously demonstrated. OBJECTIVE: The a...

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Bibliographic Details
Main Authors: Kimberley M Mellor, James R Bell, Igor R Wendt, Amy J Davidoff, Rebecca H Ritchie, Lea M D Delbridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182977?pdf=render