HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells

A major challenge in studies of human diseases involving macrophages is low yield and heterogeneity of the primary cells and limited ability of these cells for transfections and genetic manipulations. To address this issue, we developed a simple and efficient three steps method for somatic 293T cell...

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Bibliographic Details
Main Authors: Kuan-Teh Jeang, Sergei Nekhai, Xiaomei Niu, Gustavo Brito Alvim de Melo, Min Xu, Namita Kumari, Marina Jerebtsova
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Biology
Subjects:
Online Access:http://www.mdpi.com/2079-7737/1/2/175