Conjugation of Daunorubicin to Monoclonal Antihuman Sarcoma Antibody by a Novel Method

Most of the reported methods for coupling anthracycline drugs to antibody result in either a loss of pharmacological activity or yield antibodies which have lost much of their immunological specificity. The use of glutaraldehyde for coupling saves both the pharmacological and immunological activitie...

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Bibliographic Details
Main Authors: Michel Pagé, Denis Thibeault, Hélène Tremblay, Christiane Noël, Marie-Josée Perron
Format: Article
Language:English
Published: Hindawi Limited 1992-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1992/398178