Brain Gangliosides of a Transgenic Mouse Model of Alzheimer's Disease with Deficiency in GD3-Synthase: Expression of Elevated Levels of a Cholinergic-Specific Ganglioside, GT1aα
In order to examine the potential involvement of gangliosides in AD (Alzheimer's disease), we compared the ganglioside compositions of the brains of a double-transgenic (Tg) mouse model [APP (amyloid precursor protein)/PSEN1 (presenilin)] of AD and a triple mutant mouse model with an additional...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-04-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1042/AN20130006 |