MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

MRCKα is a ubiquitously expressed serine/threonine kinase involved in cell contraction and F-actin turnover, which is highly amplified in human breast cancer and part of a gene expression signature for bad prognosis. Nothing is known about the in vivo function of MRCKα. To explore MRCKα function in...

Full description

Bibliographic Details
Main Authors: Mei Qi Kwa, Rafael Brandao, Trong H. Phung, Jianfeng Ge, Giuseppe Scieri, Cord Brakebusch
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/942