Biological abnormalities of peripheral A2A receptors in a large representation of polyglutamine disorders and Huntington's disease stages

Biological abnormalities of peripheral A2A receptors in a large representation of polyglutamine disorders and Huntington's disease stages

Huntington’s disease is one of a group of hereditary neurodegenerative diseases characterized by a glutamine expansion (polyQ) in proteins which are expressed in various cell populations. In agreement with this widespread distribution, we have previously shown that A2A receptor signaling is affected...

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Bibliographic Details
Main Authors: K. Varani, A.-C. Bachoud-Lévi, C. Mariotti, A. Tarditi, M.P. Abbracchio, V. Gasperi, P.A. Borea, G. Dolbeau, C. Gellera, A. Solari, A. Rosser, J. Naji, O. Handley, M. Maccarrone, Marc Peschanski, S. DiDonato, E. Cattaneo
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neurobiology of Disease
Subjects:
Triplet repeat disorders
Biomarkers
A2A adenosine receptors
Huntington’s disease
HD
Spinocerebellar ataxia 1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000782

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http://www.sciencedirect.com/science/article/pii/S0969996107000782

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