Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor

Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor

The ATP-binding cassette transporters ABCG5 and ABCG8 formheterodimers that limit absorption of dietary sterols in theintestine and promote cholesterol elimination from the bodythrough hepatobiliary secretion. To identify cis-regulatoryelements of the two genes, we have cloned and analyzedtwenty-thr...

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Bibliographic Details
Main Authors: Su Sun Back, Jinsu Kim, Daehyung Choi, Eui Sup Lee, Soo Young Choi, Kyuhyung Han
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-06-01
Series:BMB Reports
Subjects:
ABCG5
ABCG8
Cholesterol
LXR
Transcription
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMDAxMTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni02JTVEMTMwNjI1MjMxNF8lMjgzMjItMzI3JTI5Qk1CXzEyLTI0Ni5wZGY=

Internet

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