Jumonji C Demethylases in Cellular Senescence

Senescence is a stable cell cycle arrest that is either tumor suppressive or tumor promoting depending on context. Epigenetic changes such as histone methylation are known to affect both the induction and suppression of senescence by altering expression of genes that regulate the cell cycle and the...

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Bibliographic Details
Main Authors: Kelly E. Leon, Katherine M. Aird
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Genes
Subjects:
p53
Online Access:http://www.mdpi.com/2073-4425/10/1/33