Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

Biomolecular condensates, which assemble via the process of liquid–liquid phase separation (LLPS), are multicomponent compartments found ubiquitously inside cells. Experiments and simulations have shown that biomolecular condensates with many components can exhibit multilayered organizations. Using...

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Bibliographic Details
Main Authors: Ignacio Sanchez-Burgos, Jorge R. Espinosa, Jerelle A. Joseph, Rosana Collepardo-Guevara
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
protein liquid–liquid phase separation
multicomponent condensates
minimal protein model
multilayered condensates
multiphase condensates
Online Access:https://www.mdpi.com/2218-273X/11/2/278

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https://www.mdpi.com/2218-273X/11/2/278

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