Is Innervation of the Neuromuscular Junction at the Diaphragm Modulated by sGC/cGMP Signaling?

Is Innervation of the Neuromuscular Junction at the Diaphragm Modulated by sGC/cGMP Signaling?

We previously reported NO/sGC signaling in the upper respiratory pathway, receiving input from the respiratory neurons of the brainstem to phrenic motoneurons in the C3–C6 spinal cord. In order to assess whether innervation of the neuromuscular junction (NMJ) at the diaphragm is modulated by sGC/cGM...

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Bibliographic Details
Main Authors: Nadežda Lukáčová, L’udmila Hricová, Alexandra Kisucká, Štefánia Papcunová, Katarína Bimbová, Mária Bačová, Jaroslav Pavel, Martin Marsala, Ivo Vanický, Zuzana Dzurjašková, Stanislav Matéffy, Viktória Lukáčová, Andrea Stropkovská, Ján Gálik
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
sGC/cGMP signaling
lower respiratory pathway
rat phrenic nerve ligation
phrenic nerve axonal degeneration
diaphragm neuromuscular junctions
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00700/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00700/full

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