Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

Abstract Background Infections with helminths cause an enormous disease burden in billions of animals and plants worldwide. Large scale use of anthelmintics has driven the evolution of resistance in a number of species that infect livestock and companion animals, and there are growing concerns regar...

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Bibliographic Details
Main Authors: Stephen R. Doyle, Christopher J. R. Illingworth, Roz Laing, David J. Bartley, Elizabeth Redman, Axel Martinelli, Nancy Holroyd, Alison A. Morrison, Andrew Rezansoff, Alan Tracey, Eileen Devaney, Matthew Berriman, Neil Sargison, James A. Cotton, John S. Gilleard
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
Haemonchus contortus
Ivermectin
Drug resistance
Genome sequencing
Population genetics
Genetic mapping
Online Access:http://link.springer.com/article/10.1186/s12864-019-5592-6

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http://link.springer.com/article/10.1186/s12864-019-5592-6

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