Computational Modeling as a Tool to Investigate PPI: From Drug Design to Tissue Engineering

Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the features of PPI binding surfaces make the use of structure-based drug discovery methods very challengi...

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Bibliographic Details
Main Authors: Juan J. Perez, Roman A. Perez, Alberto Perez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.681617/full