CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).

CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).

Primary Amoebic Meningoencephalitis (PAM) is caused by Naegleria fowleri, a free-living amoeba that occasionally infects humans. While considered "rare" (but likely underreported) the high mortality rate and lack of established success in treatment makes PAM a particularly devastating infe...

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Bibliographic Details
Main Authors: Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podust
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5746216?pdf=render

Internet

http://europepmc.org/articles/PMC5746216?pdf=render

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