SGO1 maintains bovine meiotic and mitotic centromeric cohesions of sister chromatids and directly affects embryo development.

Shugoshin (SGO) is a critical factor that enforces cohesion from segregation of paired sister chromatids during mitosis and meiosis. It has been studied mainly in invertebrates. Knowledge of SGO(s) in a mammalian system has only been reported in the mouse and Hela cells. In this study, the functions...

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Bibliographic Details
Main Authors: Feng-Xia Yin, Guang-Peng Li, Chun-Ling Bai, Yang Liu, Zhu-Ying Wei, Cheng-Guang Liang, Thomas D Bunch, Lin-Sen Zan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3760824?pdf=render