Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization

Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization

During silicosis, immune cells, including macrophages, T cells, B cells, and NK cells, participate in fibrosis development through alteration of the immune status. Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with a key role in initiating immune responses and sustaining imm...

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Bibliographic Details
Main Authors: Suna Liu, Changfu Hao, Lei Bao, Dehua Zhao, Hongyi Zhang, Jianyong Hou, Di Wang, Huiting Chen, Feifei Feng, Wu Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
silica
silicosis
alveolar macrophages
phagocytosis
Th2 polarization
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00787/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00787/full

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