Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection

Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection

The reasons behind the clinical variability of SARS-CoV-2 infection, ranging from asymptomatic infection to lethal disease, are still unclear. We performed genome-wide transcriptional whole-blood RNA sequencing, bioinformatics analysis and PCR validation to test the hypothesis that immune response-r...

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Bibliographic Details
Main Authors: Petros P. Sfikakis, Kleio-Maria Verrou, Giannis Ampatziadis-Michailidis, Ourania Tsitsilonis, Dimitrios Paraskevis, Efstathios Kastritis, Evi Lianidou, Paraskevi Moutsatsou, Evangelos Terpos, Ioannis Trougakos, Vasiliki Chini, Menelaos Manoloukos, Panagiotis Moulos, Georgios A. Pavlopoulos, George Kollias, Pantelis Hatzis, Meletios A. Dimopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
innate immunity
anti-SARS-CoV2 antibody
asympomatic
RNAseq
whole-blood
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.746203/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.746203/full

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