Patterned Drug-Eluting Coatings for Tracheal Stents Based on PLA, PLGA, and PCL for the Granulation Formation Reduction: In Vivo Studies

Patterned Drug-Eluting Coatings for Tracheal Stents Based on PLA, PLGA, and PCL for the Granulation Formation Reduction: In Vivo Studies

Expandable metallic stent placement is often the only way to treat airway obstructions. Such treatment with an uncoated stent causes granulation proliferation and subsequent restenosis, resulting in the procedure’s adverse complications. Systemic administration of steroids drugs in high dosages slow...

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Bibliographic Details
Main Authors: Olga A. Sindeeva, Ekaterina S. Prikhozhdenko, Igor Schurov, Nikolay Sedykh, Sergey Goriainov, Arfenya Karamyan, Ekaterina A. Mordovina, Olga A. Inozemtseva, Valeriya Kudryavtseva, Leonid E. Shchesnyak, Rimma A. Abramovich, Sergey Mikhajlov, Gleb B. Sukhorukov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
tracheal stents
drug-eluting coatings
microchamber array
PLA
PCL
PLGA
Online Access:https://www.mdpi.com/1999-4923/13/9/1437

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https://www.mdpi.com/1999-4923/13/9/1437

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