Bradykinin release avoids high molecular weight kininogen endocytosis.

Human H-kininogen (120 kDa) plays a role in many pathophysiological processes and interacts with the cell surface through protein receptors and proteoglycans, which mediate H-kininogen endocytosis. In the present work we demonstrate that H-kininogen containing bradykinin domain is internalized and d...

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Bibliographic Details
Main Authors: Igor Z Damasceno, Katia R B Melo, Fabio D Nascimento, Daianne S P Souza, Mariana S Araujo, Sinval E G Souza, Misako U Sampaio, Helena B Nader, Ivarne L S Tersariol, Guacyara Motta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4379145?pdf=render