Cell-Autonomous Ca2+ Flashes Elicit Pulsed Contractions of an Apical Actin Network to Drive Apical Constriction during Neural Tube Closure

Neurulation is a critical period in all vertebrates and results in the formation of the neural tube, which gives rise to the CNS. Apical constriction is one of the fundamental morphogenetic movements that drives neural tube closure. Using live imaging, we show that apical constriction during the neu...

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Bibliographic Details
Main Authors: Neophytos Christodoulou, Paris A. Skourides
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715013170