Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics

Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics

Constant improvements to the Orbitrap mass analyzer, such as acquisition speed, resolution, dynamic range and sensitivity have strengthened its value for the large-scale identification and quantification of metabolites in complex biological matrices. Here, we report the development and optimization...

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Bibliographic Details
Main Authors: Pierre Barbier Saint Hilaire, Kathleen Rousseau, Alexandre Seyer, Sylvain Dechaumet, Annelaure Damont, Christophe Junot, François Fenaille
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Metabolites
Subjects:
metabolomics
high resolution mass spectrometry
Orbitrap Fusion
DDA
DIA
Online Access:https://www.mdpi.com/2218-1989/10/4/158

Internet

https://www.mdpi.com/2218-1989/10/4/158

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