Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall

Toxoplasma gondii establishes chronic infection in humans by forming thick-walled cysts that persist in the brain. Once host immunity wanes, cysts reactivate to cause severe, and often lethal, toxoplasmic encephalitis. There is no available therapy to eliminate cysts or to prevent their reactivation...

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Bibliographic Details
Main Authors: Rebekah B. Guevara, Barbara A. Fox, David J. Bzik
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mSphere
Subjects:
gra
Online Access:https://doi.org/10.1128/mSphere.00851-19