Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

Summary: AMPylation is a post-translational modification that modifies amino acid side chains with adenosine monophosphate (AMP). Recently, a role of AMPylation as a universal regulatory mechanism in infection and cellular homeostasis has emerged, driving the demand for universal tools to study this...

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Bibliographic Details
Main Authors: Dorothea Höpfner, Joel Fauser, Marietta S. Kaspers, Christian Pett, Christian Hedberg, Aymelt Itzen
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309974