Hepatitis C virus NS5A protein binds the SH3 domain of the Fyn tyrosine kinase with high affinity: mutagenic analysis of residues within the SH3 domain that contribute to the interaction
<p>Abstract</p> <p>Background</p> <p>The hepatitis C virus (HCV) non-structural 5A protein (NS5A) contains a highly conserved C-terminal polyproline motif with the consensus sequence Pro-X-X-Pro-X-Arg that is able to interact with the Src-homology 3 (SH3) domains of a v...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-02-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/5/1/24 |